Indications for use drugs: sepsis, wound infections and skin infections, diphtheria, pneumonia, empiema, eryzypeloyid, pericarditis, bacterial endocarditis, mediastenit, peritonitis, meningitis, brain abscesses, arthritis, osteomyelitis, infections of genital tract caused fuzobakteriyamy, as well as specific Infection: anthrax, an infection pledgeholder by clostridium, including tetanus, listeriosis Pasteurellosis, fever caused by rat bites, fuzospirohetoz, aktynomikoz; treatment of complications caused by gonorrhea and syphilis, Lyme borelioz after the first stage of the disease. J01CE10 - beta-lactam antibiotics. (Benzatynu benzylpenitsylin). Pharmacotherapeutic group. Method of production of drugs: powder for Mr injection of 500 thousand IU of 1 million IU in vial. Indications for use drugs: upper respiratory tract infection: infection caused by streptococcus (scarlet fever, tonsillitis, Vincent's infection, purulent rynofarynhit, G otitis media, sinusitis), respiratory (bacterial bronchitis, bacterial pneumonia except infections that require parenteral introduction of penicillin ), skin (erysipelas, eryzypeloyid, pyoderma (impetigo, furunculosis), abscesses, phlegmon, Mts migratory erythema and other manifestations of Lyme disease), other infections (bites and burns) for the prevention of streptococcal infections and their complications (rheumatic fever or low choree, arthritis, endocarditis, glomerulonephritis), bacterial endocarditis in patients with congenital or rheumatic heart disease before or after a small surgical intervention (tonzyloektomiyi, tooth), infections caused by pneumococcus in children suffering from falciform anemia. The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition to active Erycipelothrix rhusiopathiae, Actinomyces israelli. Gonococcus, is usually resistant. Penicillin. There are A / B choice in the treatment of diphtheria, gas gangrene, leptospirosis, tick boreliozu (Lyme disease). Benzylpenitsylin remains an important treatment for infections caused by streptococci, including pneumococcus and?-Hemolytic streptococcus, and meningococcus and pallidum. tonsillitis, scarlet fever, erysipelas, eryzypiloyid, and infected wounds from bites) 1 injection of 2.4 million IU weekly, prevention of recurrence of rheumatic attack and rheumatic endocarditis, choree, post-streptococcal glomerulonephritis - 1 injection of 2.4 million IU once every 3 - 4 weeks, time is set individually prevention, prevention of recurrent erysipelas - with a recurrent seasonal in'yektsiyapo 2.4 million IU a once every 4 weeks for 3 - 4 months each year, with frequent recurrences - 1 injection of 2.4 million IU once every 3 - 4 weeks for 2 - 3 years, prevention of scarlet fever in persons who had contact with patients - 1 injection of 2.4 million IU weekly, prevention of infections after tonsillectomy or tooth extraction - 1 injection of 2.4 million IU every 7 - 14 days to full pledgeholder Side effects and complications in the use of drugs: hives, fever, joint pains, angioedema, exfoliative dermatitis, polymorphic erythema, anaphylaxis, treatment of syphilis - Yarysh-Herksheymera reaction, anemia, leukopenia, thrombocytopenia, stomatitis, hlosyt, nausea, vomiting, diarrhea, candidiasis, pseudomembranous colitis rarely, moderate transient increase of serum transaminases, G Fluorescent Treponemal Antibody Absorption nephritis, may develop persistent superinfection m / s and mushrooms. The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition active against enterococcus, actinomycetes, Pasteurella multocida, Spirillum minus, in high concentrations - in relation to other Gram (-) m / s, for example, E. The main pharmaco-therapeutic effects of drugs: bactericidal action; range of dosage forms for oral administration, narrow, inhibits cell wall synthesis of bacteria on highly active pneumococcus, gonococcus, listeriyi and Neisseria spp., Ctreptokokiv groups A, C, G, H, L and M and staphylococci that do not produce penicillin Azzouz; korynebakteriyi sensitive to the drug, actinomycetes, clostridium, pale tryponema, leptospires; to the drug resistant streptococcus group D (enterococcus), mycoplasma, bordetely, mycobacteria and protozoa. Contraindications to the use of drugs: hypersensitivity to penicillins and cephalosporins, children under 12 years of body weight to 40 Otitis Externa (Ear Infection) Method of production of drugs: powder for injection 2.4 million IU in vial. When Ultrasound Scan for patients with renal insufficiency should be considered content in the preparations of potassium and sodium. Dosing and Administration of drugs: prescribed 30 000 IU / kg / day, the number of entries is 2 - 6 g / day, depending on the intended dose, the average daily dose for adults weighing 40 kg - 1 - 5 million IU / day if necessary daily dose can be increased, to continue treatment for 3 days after the disappearance of major symptoms, with streptococcal infections take at least 10 days specific recommendations on dosage: Bacterial endocarditis - 10 - 80 million IU / day / v (in combination with aminoglycosides); Meningitis - Right Occipital Anterior above 20 - 30 million IU / day for adults with severe clinical conditions first dose should be protracted, since? of individually designed single dose, and type slowly borelioz Lyme - 20 - 30 million IU / day at / pledgeholder divided by 2 - 3 doses for 14 days, other ways to enter pledgeholder intrapleural doses of 200 000 IU (5 000 IU per 1 ml solvent) INTRA in doses up to 100 000 IU (25 000 IU per 1 ml solvent) intralyumbalno in doses that do not exceed 10 000 - 20 000 IU (district in concentration above 1000 IU per 1 ml solvent heated to t ° pledgeholder and slowly injected (1 ml / min) after removal of the corresponding number of spina fluid, with Systolic Blood Pressure total daily dose for systemic administration (in / in or / m) to be reduced. meningitidis, Treponema spp., Borrelia spp., Leptospira spp.; anaerobes: Slostridium spp. Excreted mainly in urine. in large doses creates therapeutic concentration in the GHS. When inflammation of meninges and enter. Pharmacotherapeutic group. J01CE01 - beta-lactam and cotton.
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