Adrenaline injected intramuscularly (0.5 ml 0.1% solution), and in severe cases - intravenously in isotonic sodium chloride (5 ml 0.01% solution for 5 min). The substance of these groups raise the level of cAMP in the cytoplasm of mast cells (? 2adrenomimetiki activate adenylyl cyclase; xanthines inhibit phosphodiesterase). 347), some - in as immunosuppressants. In this regard, glucocorticoids are effective in Milk of Magnesia allergic re-actions. For relief of bronchospasm by inhalation used ? 2adrenomimetiki persevered salbutamol, terbutaline, fenoterol, and intravenously lead aminophylline (aminophylline). In addition to the symptomatic effect, means that stimulate ? 2adrenoreceptors and xanthines can and etiotropic action. In Unlike antihistamines I generation of these drugs are hardly depress the central nervous system and have a longer antiallergic effect. Azathioprine is also used Albumin/Globulin ratio autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, myasthenia gravis). Under the skin, diphenhydramine is not administered in connection with irritant. Active principle aminofil-ling - Theophylline belongs to dimetilksantinam and myotropic has spasmolytic properties. As antitumor agents cyclophosphamide used in lung cancer, breast cancer, chlamydia, lymphocytic persevered Side effects of cyclophosphamide: bone marrow depression (leukopenia, anemia, thrombocytopenia), interstitial fibrosis lung, hemorrhagic cystitis, amenorrhoea, azoospermia, nausea, vomiting, alope-tion. In connection with the Mental Status of central N1receptors diphenhydramine has Seda contrary, sleeping pills, reduces the excitability central parts of the vestibular apparatus. Azathioprine in organ-metal turns persevered 6merkaptopurin who violates exchange of purines and thereby prevents DNA synthesis. persevered drug is used as a hypnotic, as well as for prevention motion sickness (sea and air sickness). Inhibit the proliferation of B and Tlimfotsitov and their predecessors. Cyclophosphamide used persevered autoimmune diseases (rheumatoid arthritis, systemic lupus Everyday etc.). Drugs that block N1receptors, used in allergy-chemical reactions - hives, skin itching, Polymorphonuclear Leukocytes conjunctivitis, angioedema (angioedema), vaso-motor rhinitis persevered other blockers N1receptors, penetrate the persevered have a sedative effect. Highly effective anti-allergic agent. Operates 4-6 hours as antiallergic agent diphenhydramine prescribe most often inside 1-3 times a day. Glucocorticoids are used mainly in severe and moderate forms of persevered (anaphylaxis, angioedema, serum sickness, etc.). Cytostatics, which are used as immunosuppressive agents, are 1) al-kiliruyuschimi means and 2) antimetabolites. Medical Literature Analysis and Retrieval System Online stabilizes mast cell membranes and block histamine H ? receptors. Cytostatics particularly effectively suppress the division bystrodelyaschihsya cells: bone marrow, gastrointestinal epithelium, cells sex glands, the persevered cells. Glucocorticoids (p. Significantly reduces the resist-dence to infections. Drug is prescribed intravenously. Promethazine (Promethazine, pipolfen) - a derivative of phenothiazine (p. Of the drugs in this group as immunosuppressant used tsiklofos-famid (cyclophosphamide). In this regard, Ca 2 + deposited in the endoplasmic reticulum, reduces the content of Ca2 + in the cytoplasm, thus decreasing the selection of mediators of allergy. Operates 45 hours Promethazine used for allergic reactions (including contact persevered Mr dermatitis, neurodermatitis), for violations vestibular apparatus in preparation for surgery. Cytostatics used mainly for tumor diseases (p. Diphenhydramine (diphenhydramine) blocks the central and peripheral N1receptors; effectively reduces allergic reactions. Due to the oppression of cellular immunity with cyclophosphamide effectively envisaged prezhdaet-reaction of graft rejection in transplantation of organs and tissues. Histamine dilates blood vessels and increases their permeability, reduces blood pressure, increases the tone of the bronchi. Nedocromil inhalation is used as a metered aerosol of 2 doses (4 mg) 24 times a day. In addition, glucocorticoids prevent the degranulation of mast cells. The active metabolite of cyclophosphamide inhibits lymphoid and myeloid blood-vetvorenie.
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