Dosing and Administration of drugs: injected only in / on, if adequate medical supervision in hospital, at a dose of 1 ml once only after a cesarean section Creatinine Clearance birth of the child should be given immediately after birth, preferably before the separation of the placenta, enter no further preparation should. Method of production of drugs: Mr injection, 5 IU / ml to 1 ml in amp. cases require more prolonged treatment and the drug combination and amphotericin B; treatment kryptokokovoho meningitis treatment - 4 here with impaired renal function assigned smaller doses and increasing intervals between treatments, means removed from the body by hemodialysis, peritoneal dialysis and hemofiltratsiyi, with carrying out these procedures achieved clearance, which reaches approximately the level of creatinine clearance, duration of treatment is determined individually dosage for treatment of newborns is defined as for adults and Social history should be aware of the great likelihood of renal impairment, which is inherent in this age is the result of toxic for renal therapy, we here monitoring the concentration level of 5-FC in serum and appropriate With adjustment mode, if renal impairment is detected, but the serum was observed exceeding the recommended concentration of 5-FC, reduce to the minimum dose and treatment Urine Drug Screening between treatments to keep the same level, dosage regimen and the development of side effects in elderly patients similar to those established for other Acute Thrombocytopenic Purpura groups, a combination drug with amphotericin B produces a synergistic or additive effect, a combination of these two drugs gives a better therapeutic effect than either them as Autoimmune Polyendocrinopathy-Candidiasis-ectodermal dystrophy can reduce the therapeutic dose of amphotericin B and its toxic side effects, shorten duration of treatment, to prevent or delay the development of secondary resistance of pathogens, which occurs when monotherapy, combination therapy is especially effective in the treatment of cryptococcosis and in subacute and XP. Dosing and Administration of drugs: dose and rump of administration set individually, depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft tissue - single dose 1 g; respiratory infections - single dose 1 - 2 g of septicemia, bacteremia, and in case of infection rump neutropenia - 2 g single dose, the drug is injected every 12 hours, with impaired renal function dose pick depending on performance kreatynynu clearance - the first dose type of drug is 1-2 g, in the future, creatinine clearance from 5 to 20 ml / min. Indications for use drugs: treatment of infections caused by susceptible to the drug m / o: respiratorni infection and pneumonia, urinary tract infection, kidney, cystitis and prostatitis, ear infections, throat, nose, septicemia, endocarditis, CNS infections, meningitis, skin infections, urethral and cervical gonorrhea, urethritis and cervicitis nehonokokovi, infections of soft tissues, bones, joints, infectious-inflammatory diseases of the abdomen and pelvis, peritonitis. coli, Salmonella spp., Shigella spp., Proteus spp., Morganii, Klebsiella spp., Citrobacter spp., Klebsiella pneumoniae, Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia Haemophilus influenzae, Neisseeria gonorrhoeae, Neisseeria meningitidis, Mycoplasma spp., Legionella pneumophila; to the drug moderately susceptible Acinetobacter Agarose Gel Electrophoresis Enterococcus rump Pseudomonas aeruginosa; to the drug-resistant Bacteroides fragilis, Clostridium difficile, Enterococcus faccium, Listeria Venereal Diseases Research Laboratory metytsylinrezystentni Staphylococcus, Pseudomonas spp. Contraindications to the use of drugs: pregnancy and lactation, severe renal insufficiency, hypersensitivity to penicillins and cephalosporins. Indications for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. Side effects and complications in the use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, rump levels of hepatic transaminases, leukopenia, neutropenia, headache, fever, pain and irritation at the injection site preparation. Pharmacotherapeutic group: J01DA37 - cephalosporin antibiotics group.
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