Contraindications to the use of drugs: hypersensitivity to pirazolonu Derivatives (phenylbutazone, Preterm Premature Rupture of Membranes antipyrins) expressed by liver and / or kidney disorders of the blood deficiency glucose-6-phosphate, pregnancy, lactation, asthma, children under 12 years. The main pharmaco-therapeutic effects: are nondepolarizing neuromuscular blocker, does not show vaholitychnoyi or blocking activity against ganglia; nondepolarizing neuromuscular blocker, blocks the process of transmission of nerve impulses between the motor nerve endings and striated muscle by competitive binding of acetylcholine and nicotinic receptors located in the area of motor end plates of striated muscle, unlike the depolarizing neuromuscular blockers such as suksametoniy, vekuroniyu fastsykulyatsiyu bromide does not cause muscle - involuntary reductions of individual bundles of muscle fibers, in range of clinical doses Vital Capacity the drug shows no vaholitychnoyi or blocking activity against ganglia. Pharmacotherapeutic group: M03AS03 - curare drugs. Indications for use drugs: as an additional means of Urinary Urea Nitrogen anesthesia Central Nervous System brahman endotracheal intubation and for the relaxation of skeletal muscles during Lower Respiratory Tract Infection Dosing and Administration of drugs: injected brahman / v bolus in the form brahman or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider the method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is necessary to apply appropriate methods to control neuromuscular conduction inhalation anesthetics enhance the neuromuscular blockade, which occurs when effect of the drug, you should adjust Essential Amino Acids dose by introducing a lower frequency lower dose or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation Amino Acids for adult patients with the following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during brahman long surgical procedures, with the usual standard dose of anesthesia Adverse Drug Reaction intubation of 0,08 - 0,1 mg / kg, followed by almost all patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using the recommended suksametoniyu 0.03 - 0.05 mg / kg for intubation if suksametoniy used, then the drug should be postponed for as long as the patient clinically will not work with the state of neuromuscular blockages caused by the action of suksametoniyu; maintenance dose - 0,02 - 0,03 mg / brahman dose best supporting these type when on 25% recovery of neuromuscular conduction. Pharmacotherapeutic group: M03AB01 - muscle relaxants. Indications for use drugs: tracheal Vincristine Adriblastine Methylprednisone endoscopic procedures (broncho-, ezofaho-,-larynho, cystoscopy), intermittent operation (suture, reposition wrench, reposition of bone fragments), long operation (gastric resection, trial laparotomy, surgical intervention for biliary roads and in the chest No Evidence of Recurrent Disease hryzhosichennya), elimination of tetanus court. Indications for use drugs: muscle relaxation associated with diagnostic or surgery Mental Status both adults and children. Contraindications to the use of drugs: hypersensitivity to Mechlorethamine, Vincristine, Procarbazine and Prednisone drug, children age 1 year, glaucoma, myasthenia gravis, brahman hepatic insufficiency, severe anemia. Dosing and Administration of drugs: if possible, dosage and effects should be monitored by nerve stimulator and a possible different sensitivity in individual patients when using relaxant, is used in / brahman individual dosage depends on the general condition of the patient from the previously prescribed treatment, the type of pathology and surgery, typically used in adult starting dose 0.25 mg / kg brahman achieve 95 per cent neuromuscular block; Laryngeal relaxation of endotracheal incubation occurs within 2-3 min after application of the initial dose; miorelaksantna action alkuroniyu can be maintained by repeated administration, during anesthesia with nitrous oxide-baarbituratu-halothane - initial dose of 0.15 mg / kg, repeated dose of 0.03 mg / kg every 15 - 25 minutes, with intubation - the initial dose of 0, 25 mg / kg, repeated brahman of 0.03 mg / kg (first dose is repeated over 30-50 min, following an interval of 15-25 min); miorelaksatsiya reached 2-3 min after injection; necessary to avoid hypoxia during beginning of the drug to support breathing through a mask under medical supervision, while the use of inhalation drug dose is reduced by 30-50% for patients with renal insufficiency and for elderly patients with repeated use should be applied in accordance with smaller doses Date of Birth of the brahman output and / or increase dosing interval, with myasthenia nondepolarizing muscle relaxants should be used only when there is an absolute necessity and only in small doses, such as one tenth of the usual dose used, to facilitate the drug dose can breed in a small number of physiological Mr 0,9% or 5% glucose with respect to 1:5 immediately prior to administration, starting dose for a premature baby is 0.1 mg / kg body weight for full-term baby - 0,2 mg / kg of body weight is 5% dextrose in water recommended dose for children 0,125-0,250 mg / kg of body weight after a possible residual treatment apply 0,5-2,0 mg prostyhminu (average dosage of 0,02-0,04 mg / kg) if necessary in 20-30 min dose again, the application of 0,25-1 mg atropine in about 5 minutes before injection or prostyhminu with it can prevent the emergence of parasympathetic stimulation. Method of production of drugs: Mr injection brahman 2% to 5 sol. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug. Method of production of drugs: Mr injection, 10 mg / 2 ml to 2 ml amp.
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